Aldolase polyclonal, anti-human, mouse, rat, zebrafish

Background:
Fructose 1,6-bisphosphate aldolase catalyses the reversible condensation of glycerone-P and glyceraldehyde 3-phosphate into fructose 1,6-bisphosphate. Fructose 1,6-bisphosphate aldolase exists as three forms: the muscle-specific Aldolase A, the liver-specific Aldolase B, and the brain-specific Aldolase C. Aldolase A, B and C arose from a common ancestral gene from which Aldo-lase B first diverged. Aldolase A is one of the most highly-conserved enzymes known, with only about 2% of the residues changing per 100 million years. Aldolase B is regulated by the hormones insulin and glucagon, and has been implicated in hereditary fructose intolerance disease. Aldolase C is a polypeptide that is exclusively expressed in Purkinje cells. Aldolase C-positive Purkinje cells are organized in the cerebellum as stripes or bands that run from anterior to posterior across the cerebellum and alternate with bands of Aldolase C-negative Purkinje cells.

Alternative Name:
ALDOA, ALDA, ALDA, Aldo1, ALDOA, ALDOA, Aldolase 1, Aldolase A, Aldolase A fructose bisphosphatase, Aldolase A fructose bisphosphate, Aldolase, fructose-bisphosphate A, Epididymis secretory sperm binding protein Li 87p, FRUCTOALDOLASE A, Fructose 1 6 bisphosphate triosephosphate lyase, Fructose bisphosphate aldolase A, Fructose bisphosphate aldolase, FRUCTOSE-1, 6-BISPHOSPHATE ALDOLASE A, Fructose-bisphosphate aldolase A, Fructose-bisphosphate aldolase A Muscle-type, GSD12, HEL S 87p, Lung cancer antigen NY LU 1, Lung cancer antigen NY-LU-1, MGC10942, MGC17716, MGC17767, Muscle type aldolase, Muscle-type aldolase, RNALDOG5,

Application Dilution:
WB:1:500-1:2,000
ICC/IF:1:50-1:200
IHC:1:50-1:200

Specificity: Aldolase polyclonal antibody detects endogenous levels of Aldolase protein.

Immunogen:
Recombinant protein

MW: 39 kDa

Swiss-Prot: P04075(Human) P05064(Mouse) P05065(Rat)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.