ALK polyclonal (C-term), anti-human
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In stock
SKU
AC-AP7600b
Catalog Number: AC-AP7600b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1513-1514
Applications: IHC-P
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB1513-1514
Applications: IHC-P
Datasheet
Request Information
Background:
ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2;5)(p23;q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
Other Names:
ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, CD246, ALK
Target/Specificity:
This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1591~1620 amino acids from the C-terminal region of human ALK.
Antigen Region:
1591-1620
Antigen Type: Synthetic Peptide
Gene Name: ALK {ECO:0000303|PubMed:9174053, ECO:0000312|HGNC:HGNC:427}
Gene ID: 238
Primary Accession: Q9UM73
NCBI Accession: NP_004295.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ALK, a member of the insulin receptor subfamily of Tyr protein kinases, is an orphan receptor. It appears to play an important role in the normal development and function of the nervous system. This Type I membrane protein is expressed in brain and CNS and in the small intestine and testis, but not in normal lymphoid cells. A form of non-Hodgkin's lymphoma is characterized by a chromosomal translocation t(2;5)(p23;q35) that involves NPM1 and ALK. The protein contains 1 LDL-receptor class A domain and 2 putative MAM domains.
Other Names:
ALK tyrosine kinase receptor, Anaplastic lymphoma kinase, CD246, ALK
Target/Specificity:
This ALK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1591~1620 amino acids from the C-terminal region of human ALK.
Antigen Region:
1591-1620
Antigen Type: Synthetic Peptide
Gene Name: ALK {ECO:0000303|PubMed:9174053, ECO:0000312|HGNC:HGNC:427}
Gene ID: 238
Primary Accession: Q9UM73
NCBI Accession: NP_004295.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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