ALOX15 Polyclonal Antibody

Background:
Arachidonate 15-lipoxygenaseis anenzymethat in humans is encoded by theALOX15gene. Non-heme iron-containing dioxygenase that catalyzes the stereo-specific peroxidation of free and esterified polyunsaturated fatty acids generating a spectrum of bioactive lipid mediators. Converts arachidonic acid into 12-hydroperoxyeicosatetraenoic acid/12-HPETE and 15-hydroperoxyeicosatetraenoic acid/15-HPETE. Also converts linoleic acid to 13-hydroperoxyoctadecadienoic acid. May also act on (12S)-hydroperoxyeicosatetraenoic acid/(12S)-HPETE to produce hepoxilin A3.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
15 lipoxygenase 1, 15 LIPOXYGENASE RETICULOCYTE ARACHIDONATE, 15 LOX, 15 LOX 1, 15-LOX, 15LOX 1, ALOX15, Arachidonate 15 lipoxygenase, Arachidonate 15-lipoxygenase, Arachidonate omega 6 lipoxygenase, Arachidonate omega-6 lipoxygenase, LOG15, LOX15

Immunogen: Synthetic peptide of human ALOX15

Swissprot: P16050
Gene Accession: NP_001131

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-27354/sc-32940