ALOX15B Polyclonal Antibody

Background:
This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
ALOX15B, 15-LOX-2

Immunogen: Recombinant fusion protein of human ALOX15B (NP_001132.2).

Swissprot: O15296
Gene ID: 247

Calculated MW: 67 kDa/69 kDa/72 kDa/75 kDa
Observed MW: 76 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.