ALOX5 polyclonal, anti-human

ALOX5 polyclonal, anti-human

€455.00
In stock
SKU
AC-ABO10959
Catalog Number: AC-ABO10959
Size: 100 µg
Isotype: Rabbit IgG
Applications: WB, IHC-P
Datasheet
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Description: Rabbit IgG polyclonal antibody for Arachidonate 5-lipoxygenase(ALOX5) detection. Tested with WB, IHC-P in Human.Protein Name: Arachidonate 5-lipoxygenase(5-LO/5-lipoxygenase)

Protein Function:
Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes. .

Other Names: Arachidonate 5-lipoxygenase, 5-LO, 5-lipoxygenase, 1.13.11.34, ALOX5, LOG5

Subcellular Localization: Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein. Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-272. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.

Gene ID: 240

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ALOX5 (650-667aa AERNKKKQLPYYYLSPDR), different from the related rat and mouse sequences by two amino acids.

Calculated MW: 77983

Purification: Immunogen affinity purified.

Format: Lyophilized

Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Concentration (mg/ml): Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
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