ALOX5AP polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP7897c
Catalog Number: AC-AP7897c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17169
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB17169
Applications: IHC-P, WB
Datasheet
Request Information
Background:
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
Other Names:
Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein, ALOX5AP, FLAP
Target/Specificity:
This ALOX5AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from the Central region of human ALOX5AP.
Antigen Region:
86-117
Antigen Type: Synthetic Peptide
Gene Name: ALOX5AP
Gene ID: 241
Primary Accession: P20292
NCBI Accession: NP_001191335.1;NP_001620.2
Other Accession: P20291; P30357; P30356; P30355; Q2PG08; Q148F2; P30358
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
ALOX5AP is a protein which, with 5-lipoxygenase, is required for leukotriene synthesis. Leukotrienes are arachidonic acid metabolites which have been implicated in various types of inflammatory responses, including asthma, arthritis and psoriasis. This protein localizes to the plasma membrane. Inhibitors of its function impede translocation of 5-lipoxygenase from the cytoplasm to the cell membrane and inhibit 5-lipoxygenase activation.
Other Names:
Arachidonate 5-lipoxygenase-activating protein, FLAP, MK-886-binding protein, ALOX5AP, FLAP
Target/Specificity:
This ALOX5AP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-117 amino acids from the Central region of human ALOX5AP.
Antigen Region:
86-117
Antigen Type: Synthetic Peptide
Gene Name: ALOX5AP
Gene ID: 241
Primary Accession: P20292
NCBI Accession: NP_001191335.1;NP_001620.2
Other Accession: P20291; P30357; P30356; P30355; Q2PG08; Q148F2; P30358
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
| Is Featured? | No |
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