alpha 1 Antichymotrypsin polyclonal, anti-human

Quantity: 100 µg

Background:
Alpha 1-antichymotrypsin, also called serpin peptidase inhibitor, clade A(alpha-1 antiproteinase, antitrypsin), member 3 or GIG24 is an alpha globulin glycoprotein that is a member of the serpin superfamily. In humans, it is encoded by the SERPINA3 gene. This gene is mapped to 14q32.13. The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Description:
Rabbit IgG polyclonal antibody for Alpha-1-antichymotrypsin (SERPINA3) detection. Tested with WB, IHC-P in Human.

Synonyms:
SERPINA3 antibody, AACT antibody, AACT_HUMAN antibody, ACT antibody, Alpha 1 Antichymotrypsin 1 antibody, Alpha 1 Antichymotrypsin 2 antibody, Alpha 1 Antichymotrypsin 3 antibody, Alpha 1 Antitrypsin Deficiency antibody, Alpha-1-antichymotrypsin His-Pro-less antibody, Anti Elastase antibody, Antichymotrypsin antibody, Cell growth inhibiting gene 24/25 protein antibody, Cell growth-inhibiting gene 24/25 protein antibody, Clade A(Alpha 1 Antiproteinase Antitrypsin) antibody, GIG24 antibody, GIG25 antibody, Growth inhibiting protein 24 antibody, Growth inhibiting protein 25 antibody, MGC88254 antibody, PI1 antibody, Protease Inhibitor 1 antibody, Serine(or Cysteine) Proteinase Inhibitor antibody, Serine(or cysteine) proteinase inhibitor clade A(alpha 1 antiproteinase, antitrypsin) member 3 antibody, Serine(or cysteine) proteinase inhibitor clade A member 3 antibody, Serine proteinase inhibitor clade A member 3 antibody, Serpin A3 antibody, Serpin peptidase inhibitor clade A(alpha 1 antiproteinase antitrypsin) member 3 antibody, SERPINA1 antibody, SERPINA2 antibody, SERPINA3 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human alpha 1 Antichymotrypsin(218-232aa EMPFDPQDTHQSRFY).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.