alpha 1 Fetoprotein rabbit polyclonal, anti-human

Backgroud: Alpha-fetoprotein (AFP) is a 65 kDa glycoprotein found in the mammalian fetal liver, yolk sac, and GI tract. In normal adult cells, p53 binds to the repressor region of the AFP gene, thereby blocking transcription. Mutations in both p53 and β-catenin are associated with aberrant expression of AFP. Research studies have shown that elevated serum AFP levels are predictive of hepatocellular carcinoma .

Synonyms: Alpha-fetoprotein, Alpha-1-fetoprotein, Alpha-fetoglobulin

Gene Name: AFP

Gene ID: 174

SwissProt ID: P02771

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.