Alpha-Conotoxin GI Peptide

Alpha-Conotoxin GI Peptide

€194.00
In stock
SKU
350459
Catalog Number: 350459
Size: 1 mg
Datasheet
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Protein Family: Hormones, Receptors and Channels

Pathway and Disease: Nervous and Sensory Systems, Signaling Molecules and Interactions

Alternate Names: Alpha-conotoxin GIA; alpha-conotoxin GI

Accession No.: P01519

Description:
Alpha-conotoxin GI is a 13-aa toxin isolated from the cone snail Conus geographus venom. Alpha-conotoxin GI is a potent reversible blocker of the alpha/delta nicotinic acetylcholine channel receptors (nAChR). Alpha-conotoxin GI allows to distinguish between the two agonist sites as it binds 10,000-fold more tightly to the alpha/delta site than the alpha/gamma site excepted in Torpedo which is the reverse.

Format:
Each vial contains 1 mg of lyophilized solid packaged under an inert gas and supplied as a trifluoroacetate salt.

MW: 1433.63 g/mol

Sequence:
H-Glu-Cys-Cys-Asn-Pro-Ala-Cys-Gly-Arg-His-Tyr-Ser-Cys-NH2 (Cys2-Cys7, Cys3-Cys13) or H-ECCNPACGRHYSC-NH2 (Cys2-Cys7, Cys3-Cys13)

Composition:
C55H76N20O18S4

Purity:
> 95% by HPLC

Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.

Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, aliquot and store at -20°C.
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