alpha Lactalbumin polyclonal, anti-human

Quantity: 100 µg

Background:
LALBA(lactalbumin, alpha or alpha-lactalbumin) is a protein that in humans is encoded by the LALBA gene. The LALBA gene is mapped on 12q13.11. alpha-Lactalbumin is an important whey protein in cow's milk(1 g/l), and is also present in the milk of many other mammalian species. In primates, alpha-lactalbumin expression is upregulated in response to the hormone prolactin and increases the production of lactose. alpha-Lactalbumin forms the regulatory subunit of the lactose synthase(LS) heterodimer and beta-1, 4-galactosyltransferase(beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transferring galactose moieties to glucose. As a multimer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of human alpha-lactalbumin that may form in acidic environments such as the stomach, called HAMLET, probably induces apoptosis in tumor and immature cells.

Description:
Rabbit IgG polyclonal antibody for Alpha-lactalbumin (LALBA) detection. Tested with WB, IHC-P in Human.

Synonyms:
a-LACTA antibody, alfaLA antibody, Alpha-lactalbumin antibody, Lactalbumin alpha antibody, Lactose synthase B protein antibody, LALBA antibody, LALBA_HUMAN antibody, Lysozyme-like protein 7 antibody, LYZL7 antibody, MGC138521 antibody, MGC138523 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human alpha Lactalbumin(20-37aa KQFTKCELSQLLKDIDGY).

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.