alpha Smooth Muscle Actin (clone 3G2) mouse monoclonal, anti-human, mouse, rat

Backgroud: Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.

Synonyms: ACTA2, ACTSA, ACTVS, GIG46, Actin, aortic smooth muscle, Alpha-actin-2, Cell growth-inhibiting gene 46 protein, α-SMA

Gene Name: ACTA2

Gene ID: 59

SwissProt ID: P62736

Purification: Affinity Purified

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.