ALPP monoclonal (N-term), anti-human
€0.00
In stock
SKU
AC-AM2022b
Catalog Number: AC-AM2022b
Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 421CT8.1.1
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1
Clone Name: 421CT8.1.1
Applications: WB
Datasheet
Request Information
Background:
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Other Names:
Alkaline phosphatase, placental type, Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, PLAP-1, ALPP, PLAP
Target/Specificity:
This ALPP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human ALPP.
Antigen Region:
56-83
Antigen Type: Synthetic Peptide
Gene Name: ALPP (HGNC:439)
Gene ID: 250
Primary Accession: P05187
NCBI Accession: NP_001623.3
Other Accession: P10696; NP_001623.3
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme, also referred to as the heat stable form, that is expressed primarily in the placenta although it is closely related to the intestinal form of the enzyme as well as to the placental-like form. The coding sequence for this form of alkaline phosphatase is unique in that the 3' untranslated region contains multiple copies of an Alu family repeat. In addition, this gene is polymorphic and three common alleles (type 1, type 2 and type 3) for this form of alkaline phosphatase have been well characterized.
Other Names:
Alkaline phosphatase, placental type, Alkaline phosphatase Regan isozyme, Placental alkaline phosphatase 1, PLAP-1, ALPP, PLAP
Target/Specificity:
This ALPP antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 56-83 amino acids from the N-terminal region of human ALPP.
Antigen Region:
56-83
Antigen Type: Synthetic Peptide
Gene Name: ALPP (HGNC:439)
Gene ID: 250
Primary Accession: P05187
NCBI Accession: NP_001623.3
Other Accession: P10696; NP_001623.3
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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