ALS rabbit polyclonal, anti-human, mouse, rat

Backgroud: The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Mar 2009],function:Involved in protein-protein interactions that result in protein complexes, receptor-ligand binding or cell adhesion.,similarity:Contains 20 LRR (leucine-rich) repeats.,subunit:Forms a ternary complex of about 140 to 150 kDa with IGF-I or IGF-II and IGFBP-3.,tissue specificity:Plasma.,

Synonyms: IGFALS, ALS, Insulin-like growth factor-binding protein complex acid labile subunit, ALS

Gene Name: IGFALS

Gene ID: 3483

SwissProt ID: P35858

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.