AMACR antibody (clone 1D8), anti-human
€435.00
In stock
SKU
AC-AT1128a
Catalog Number: AC-AT1128a
Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
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Size: 100 µg
Isotype: mouse IgG2b Kappa
Applications: WB, E
Request Information AC-AT1128a">Request Information
Background:
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Other Names:
Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
Antigen Type:
Recombinant Protein
Gene Name: AMACR
Gene ID: 23600
NCBI Accession: NP_001161067.1;NP_055139.4;NP_976316.1
Primary Accession: Q9UHK6
Other Accession: BC009471
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Other Names:
Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
Antigen Type:
Recombinant Protein
Gene Name: AMACR
Gene ID: 23600
NCBI Accession: NP_001161067.1;NP_055139.4;NP_976316.1
Primary Accession: Q9UHK6
Other Accession: BC009471
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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