AMACR (C-term (clone 2F3-C11-B12), anti-rat

Background:
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.

Synonyms: AMACRD, CBAS4, P504S, RACE, RM

Cellular Location: Mitochondrion Peroxisome

Immunogen:
Purified recombinant human AMACR(C-terminus) protein fragments expressed in E.coli.

Gene Symbol: AMACR(C-term)

Gene ID: 23600

Swiss prot: Q9UHK6

Calculated MW: 42kDa

Recommended dilution:
WB 1:1000, ICC 1:100

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.