AMACR polyclonal HRP, anti-human, mouse, rat

Protein Family: Enzymes

Pathway and Disease: Lipid Metabolism

Description:
Alpha-methylacyl-CoA racemase (AMACR) catalyzes the racemization of 2-methyl-branched fatty acid CoA esters. AMACR is responsible for the conversion of pristanoyl-CoA and C27-bile acyl-CoAs to their (S)-stereoisomers. Defects in AMACR are the cause of alpha-methylacyl-CoA racemase deficiency (AMACRD). AMACRD results in elevated plasma concentrations of pristanic acid C27-bile-acid intermediates. AMACRD is associated with polyneuropathy, retinitis pigmentosa, epilepsy.

Alternate Names: AMACR, Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase

Application Notes: E: 1:500-1:1,000; WB: 1:200-1:500; IHC: 1:50-1:500

Accession No.: Q9UHK6

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of mouse AMACR.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 1% BSA and 0.02% gentamicin. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Product is guaranteed 6 months from the date of shipment.