AMACR polyclonal (C-term), anti-human
€0.00
In stock
SKU
AC-AP10110b
Catalog Number: AC-AP10110b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18736
Applications: IF, FC, IHC-P, WB
Datasheet
Request Information
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB18736
Applications: IF, FC, IHC-P, WB
Datasheet
Request Information
Background:
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Other Names:
Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
Target/Specificity:
This AMACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human AMACR.
Antigen Region:
323-351
Antigen Type: Synthetic Peptide
Gene Name: AMACR
Gene ID: 23600
Primary Accession: Q9UHK6
NCBI Accession: NP_001161067.1;NP_055139.4;NP_976316.1
Other Accession: NP_976316.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Other Names:
Alpha-methylacyl-CoA racemase, 2-methylacyl-CoA racemase, AMACR
Target/Specificity:
This AMACR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 323-351 amino acids from the C-terminal region of human AMACR.
Antigen Region:
323-351
Antigen Type: Synthetic Peptide
Gene Name: AMACR
Gene ID: 23600
Primary Accession: Q9UHK6
NCBI Accession: NP_001161067.1;NP_055139.4;NP_976316.1
Other Accession: NP_976316.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
|---|
Write Your Own Review