AMD1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
S-adenosylmethionine decarboxylase(AdoMet-DC), also known as S-adenosylmethionine decarboxylase proenzyme(SAMDC), is a key enzyme in polyamine biosynthesis. It is localized to chromosome region 6q21-q22. SAMDC has an unusual distribution in polysomes from cells of T lymphocyte origin. It associates predominantly with monosomes and small polysomes with none located in the preribosomal or ribonucleoprotein pool. SAMDC is a critical regulatory enzyme of the polyamine synthetic pathway, and a well-studied drug target. Since SAMDC is a key regulatory enzyme in the synthesis of spermidine and spermine, the marked increase in SAMDC activity in the neonate and the sustained high enzyme levels throughout adulthood, imply a role for these polyamines in both development and mature brain function.

Description:
Rabbit IgG polyclonal antibody for S-adenosylmethionine decarboxylase proenzyme (AMD1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
Adenosylmethionine decarboxylase 1 antibody, AdoMetDC antibody, AMD1 antibody, DCAM_HUMAN antibody, EC 4.1.1.50 antibody, FLJ26964 antibody, S adenosylmethionine decarboxylase 1 antibody, S adenosylmethionine decarboxylase proenzyme antibody, S-adenosylmethionine decarboxylase beta chain antibody, SAMDC antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human AMD1(315-330aa FNDYNFVFTSFAKKQQ), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence at the C-terminus of human AMD1(315-330aa FNDYNFVFTSFAKKQQ), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.