AMPD1 Polyclonal Antibody

Background:
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
Adenosine monophosphate deaminase 1 (isoform M), Adenosine monophosphate deaminase 1, AMP deaminase 1, AMP deaminase isoform M, AMPD 1, AMPD, Ampd01, MAD, MADA, Myoadenylate deaminase, RATAMPD01, Skeletal muscle AMPD

Immunogen: Synthetic peptide of human AMPD1

Swissprot: P23109
Gene Accession: NP_000027

Calculated MW: 90 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:100-1:300

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-160043