Amphiphysin I Polyclonal Antibody

Background:
This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.

Research Area: Cancer, Immunology, Neuroscience

Synonyms:
Amp, AMPH 1, AMPH, AMPH, AMPH1, Amphiphysin (Stiff-Man syndrome with breast cancer 128kD autoantigen), Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen), Amphiphysin, Amphiphysin I, CG8604, Damp, dAmph, Dmel\CG8604, HGNC:471, MGC49429, Stiff man syndrome with breast cancer 128kD autoantigen, Stiff man syndrome with breast cancer 128kDa autoantigen

Immunogen: Recombinant protein of human AMPH

Swissprot: P49418
Gene Accession: BC034376

Calculated MW: 76 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-8536/sc-8537/sc-25539/sc-21710