AMPK α1 polyclonal, anti-human, mouse, rat

Background:
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Synonyms: AMPK, AMPKa1

Cellular Location: Cytoplasm

Immunogen:
A synthetic peptide of human PRKAA1

Gene Symbol: PRKAA1

Gene ID: 5562

Swiss prot: Q13131

Calculated MW: 64 kDa

Recommended dilution:
WB 1:200-1000, IHC 1:100-300,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.