AMPK beta 2 Rabbit polyclonal antibody, anti-human, mouse, rat

Background:
AMPK is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. Also regulates cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase and hormone-sensitive lipase. This is a regulatory subunit| may be a positive regulator of AMPK activity. It may also serve as an adapter molecule for the catalytic alpha-subunit.|PTM:Phosphorylated when associated with the catalytic subunit.|Belongs to the 5'-AMP-activated protein kinase beta subunit family.|subunit:Heterotrimer of an alpha catalytic subunit| a beta and a gamma non-catalytic regulatory subunits.|

Research Area: Cancer, Cardiovascular, Metabolism, Signal transduction

Synonyms: AMPKβ2, 5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year