AMPK gamma1 Polyclonal Antibody

Background:
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Research Area: Cancer, Cardiovascular, Metabolism, Signal Transduction

Synonyms:
5' AMP activated protein kinase gamma 1 subunit, 5' AMP activated protein kinase subunit gamma 1, 5''-AMP-activated protein kinase subunit gamma-1, AAKG1, AMP activated protein kinase noncatalytic gamma 1 subunit, AMPK gamma 1 chain, AMPK gamma1, AMPK subunit gamma-1, AMPKg, MGC8666, PRKAG 1, PRKAG1, Protein kinase AMP activated gamma 1 non catalytic subunit, protein kinase, AMP-activated, noncatalytic gamma-1

Immunogen: Recombinant protein of human PRKAG1

Swissprot: P54619
Gene Accession: BC000358

Calculated MW: 38 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.1 mg/mL
Dilution: WB 1:200-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-19138/sc-25793