AMPK2 polyclonal, anti-human antibody
€355.00
In stock
SKU
AC-ABV10094-100
Catalog Number: AC-ABV10094-100
Size: 100 µg
Host: Rabbit IgG
Applications: WB, E
Datasheet
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Size: 100 µg
Host: Rabbit IgG
Applications: WB, E
Datasheet
Request Information
Background:
AMPK2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart s µggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Other Names:
EC 2.7.11.1, AMPK alpha-2 chain, PRKAA2
Primary Accession: P54646
Gene Name: PRKAA2
Gene ID: 5563
Concentration (mg/ml): 0.25 mg/ml
AMPK2 is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart s µggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
Other Names:
EC 2.7.11.1, AMPK alpha-2 chain, PRKAA2
Primary Accession: P54646
Gene Name: PRKAA2
Gene ID: 5563
Concentration (mg/ml): 0.25 mg/ml
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