AMPKa2 polyclonal, anti-human

Background:
Catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators.

Synonyms: AMPK, AMPK2, PRKAA2, HMGCR kinase, ACACA kinase

Cellular Location: Nucleus

Immunogen:
A synthetic peptide of human AMPK alpha 2

Gene Symbol: AMPK alpha 2

Gene ID: 5563

Swiss prot: P54646

Calculated MW: 62kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.