AMPKβ2 Polyclonal Antibody

Background:
protein kinase AMP-activated non-catalytic subunit beta 2(PRKAB2) Homo sapiens The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013],

Alternative Names:
PRKAB2, 5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2

Immunogen: Recombinant Protein of AMPKβ2

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Observed band: 30

GeneID: PRKAB2

Storage: -20°C/1 year

NOTE: For Research Use Only