AMT polyclonal (N-term), anti-human

AMT polyclonal (N-term), anti-human

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In stock
SKU
AC-AP6739a
Catalog Number: AC-AP6739a
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB19704
Applications: FC, IHC-P, WB
Datasheet

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Background:
The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300), H protein (a lipoic acid-containing protein; MIM 238330), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase; MIM 238331). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes.

Other Names:
Aminomethyltransferase, mitochondrial, Glycine cleavage system T protein, GCVT, AMT, GCST

Target/Specificity:
This AMT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 19-45 amino acids from the N-terminal region of human AMT.

Antigen Region:
19-45

Antigen Type: Synthetic Peptide

Gene Name: AMT (HGNC:473)
Gene ID: 275
Primary Accession: P48728
NCBI Accession: NP_000472.2;NP_001158182.1;NP_001158183.1;NP_001158184.1
Other Accession: Q8CFA2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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