AMZ1 Polyclonal Antibody

Background:
AMZ1shares sequence similarity with archaeal metalloproteases called archaemetzincins, but it appears to act predominantly as a basic aminopeptidase. Inhibited by the general metalloprotease inhibitors o-phenanthroline and batimastat. Also significantly inhibited by amastatin, which is an inhibitor of aminopeptidases. Not inhibited by 4-(2-aminoethyl)-benzenesulfonyl fluoride, E-64, and TIMPS (tissue inhibitors of metalloproteinases), which are inhibitors of serine, cysteine, and matrix metalloproteases, respectively.

Research Area: Cell Biology

Synonyms:
AMZ1, Archaelysin family metallopeptidase 1, Archeobacterial metalloproteinase like protein 1, KIAA1950, Metalloproteinase like protein

Immunogen: Synthetic peptide of human AMZ1

Swissprot: Q400G9
Gene Accession: NP_597720

Calculated MW: 55 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 1.4 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.