ANAPC2 Polyclonal Antibody

Background:
A large protein complex, termed the anaphase-promoting complex (APC), or the cyclosome, promotes metaphase-anaphase transition by ubiquitinating its specific substrates such as mitotic cyclins and anaphase inhibitor, which are subsequently degraded by the 26S proteasome. Biochemical studies have shown that the vertebrate APC contains eight subunits. The composition of the APC is highly conserved in organisms from yeast to humans. The product of this gene is a component of the complex and shares sequence similarity with a recently identified family of proteins called cullins, whicHuman, Mouseay also be involved in ubiquitin-mediated degradation.

Research Area: Cell Biology

Synonyms:
anapc2, Anaphase promoting complex subunit 2, Anaphase-promoting complex subunit 2, ANC2, APC2, Cyclosome subunit 2, KIAA1406, OTTHUMP00000022692, RP11 350O14.5

Immunogen: Recombinant protein of human ANAPC2

Swissprot: Q9UJX6
Gene Accession: BC032503

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-20984