ANAPC5 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP10974c
Catalog Number: AC-AP10974c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24572
Applications: WB, FC
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24572
Applications: WB, FC
Datasheet
Request Information
Background:
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a
Other Names:
Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5, ANAPC5, APC5
Target/Specificity:
This ANAPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5.
Antigen Region:
156-185
Antigen Type: Synthetic Peptide
Gene Name: ANAPC5
Gene ID: 51433
Primary Accession: Q9UJX4
NCBI Accession: NP_001131031.1;NP_057321.2
Other Accession: NP_057321.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a
Other Names:
Anaphase-promoting complex subunit 5, APC5, Cyclosome subunit 5, ANAPC5, APC5
Target/Specificity:
This ANAPC5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 156-185 amino acids from the Central region of human ANAPC5.
Antigen Region:
156-185
Antigen Type: Synthetic Peptide
Gene Name: ANAPC5
Gene ID: 51433
Primary Accession: Q9UJX4
NCBI Accession: NP_001131031.1;NP_057321.2
Other Accession: NP_057321.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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