Androgen Receptor (clone 549CT16.1.4), anti-human antibody

Androgen Receptor (clone 549CT16.1.4), anti-human antibody

€285.00
In stock
SKU
AC-ABV11261-100
Catalog Number: AC-ABV11261-100
Size: 100 µl
Host: Mouse IgG
Applications: WB
Datasheet

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Background:
Androgens exhibit a wide range of effects on the development, maintenance and regulation of male phenotype and reproductive physiology in males. The androgen receptor (AR) is a member of the steroid superfamily of ligand-dependent transcription factors. ARs bind active testosterone (T) and dihydrotestosterone (DHT). The rates of association and dissociation of T are about 3 times more rapid than those of DHT. This difference in binding kinetics may account for the different physiological effects of T and DHT. Androgen binding results in an at least 6-fold increase in androgen receptor stability.

Other Names:
AR, DHTR, NR3C4, Androgen receptor, Dihydrotestosterone receptor, Nuclear receptor subfamily 3 group C member 4

Primary Accession: P10275

Gene Name: AR

Gene ID: 367
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