Ang-1 Polyclonal Antibody

Background:
angiopoietin 1(ANGPT1) Homo sapiens This gene encodes a secreted glycoprotein that belongs to the angiopoietin family. Members of this family play important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015],

Alternative Names:
ANGPT1, KIAA0003, Angiopoietin-1, ANG-1

Immunogen: The antiserum was produced against synthesized peptide derived from human Ang-1. AA range:158-207

Isotype: Rabbit

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration: 1 mg/ml

Observed band: 60

GeneID: ANGPT1

Storage: -20°C/1 year

NOTE: For Research Use Only