Angiopoietin 1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Angiopoietin 1 is a type of angiopoietin and is encoded by the gene ANGPT1. Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Angiopoietin-1 seems to play a crucial role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. Endothelial Tie2/Tek ligands angiopoietin-1(ANGPT1) and angiopoietin-2(ANGPT2): regional localization of the human genes to 8q22.3-q23 and 8p23.

Description:
Rabbit IgG polyclonal antibody for Angiopoietin-1 (ANGPT1) detection. Tested with WB, IHC-P, ELISA in Human, Mouse, Rat.

Synonyms:
AGP 1 antibody, AGP1 antibody, AGPT antibody, ANG 1 antibody, ANG-1 antibody, ANG1 antibody, Angiopoietin-1 antibody, Angiopoietin1 antibody, ANGP1_HUMAN antibody, ANGPT 1 antibody, ANGPT1 antibody, KIAA0003 antibody, OTTHUMP00000227592 antibody, OTTHUMP00000227599 antibody, OTTHUMP00000227600 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Angiopoietin 1(225-239aa RQTYIIQELEKQLNR), different from the related mouse and rat sequences by two amino acids.A synthetic peptide corresponding to a sequence in the middle region of human Angiopoietin 1(225-239aa RQTYIIQELEKQLNR), different from the related mouse and rat sequences by two amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat.
Predicted to work with: mouse.

Applications: WB, IHC-P, ELISA

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.