Angiopoietin 1 rabbit polyclonal, anti-human, rat

Backgroud: Binds and activates TEK/TIE2 receptor by inducing its dimerization and tyrosine phosphorylation. Plays an important role in the regulation of angiogenesis, endothelial cell survival, proliferation, migration, adhesion and cell spreading, reorganization of the actin cytoskeleton, but also maintenance of vascular quiescence. Required for normal angiogenesis and heart development during embryogenesis. After birth, activates or inhibits angiogenesis, depending on the context.

Synonyms: ANGPT1, KIAA0003, Angiopoietin-1, ANG-1

Gene Name: ANGPT1

Gene ID: 284

SwissProt ID: Q15389

Purification: Affinity Chromatography

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.