Angiotensin Converting Enzyme 1 (clone 4F3-E6-H8), anti-mouse

Background:
This gene encodes an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes - the somatic form and the testicular form that are equally active. Multiple additional alternatively spliced variants have been identified but their full length nature has not been determined.

Synonyms: ACE1, CD143, DCP, DCP1, ACE1, CD143, DCP, DCP1, ICH, MVCD3

Cellular Location: Cell membrane Cytoplasm Secreted Single-pass type I membrane protein

Immunogen:
Purified recombinant human Angiotensin Converting Enzyme 1 protein fragments expressed in E.coli.

Gene Symbol: Angiotensin Converting Enzyme 1

Gene ID: 1636

Swiss prot: P12821

Calculated MW: 190kDa

Recommended dilution:
WB 1:1000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.