ANGPT1 Polyclonal Antibody

Background:
Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Research Area: Cancer, Cardiovascular, Metabolism

Synonyms:
AGP 1, AGP1, AGPT, ANG 1, ANG, ANG-1, ANG1, Angiopoietin-1, Angiopoietin1, ANGP1, ANGPT 1, Angpt1, KIAA0003, OTTHUMP00000227592, OTTHUMP00000227599, OTTHUMP00000227600

Immunogen: Recombinant protein of human ANGPT1

Swissprot: Q15389
Gene Accession: BC029406

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: IHC 1:50-1:200

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-6319/sc-6320/sc-8357