ANGPTL4 polyclonal, anti-human, mouse

Background:
This gene encodes a glycosylated, secreted protein containing a C-terminal fibrinogen domain. The encoded protein is induced by peroxisome proliferation activators and functions as a serum hormone that regulates glucose homeostasis, lipid metabolism, and insulin sensitivity. This protein can also act as an apoptosis survival factor for vascular endothelial cells and can prevent metastasis by inhibiting vascular growth and tumor cell invasion. The C-terminal domain may be proteolytically-cleaved from the full-length secreted protein. Decreased expression of this gene has been associated with type 2 diabetes. Alternative splicing results in multiple transcript variants. This gene was previously referred to as ANGPTL2 but has been renamed ANGPTL4.

Synonyms: ARP4, FIAF, HARP, HFARP, NL2, PGAR, TGQTL, UNQ171, pp1158

Cellular Location: Secreted extracellular matrix extracellular space

Immunogen:
Recombinant protein of human ANGPTL4

Gene Symbol: ANGPTL4

Gene ID: 51129

Swiss prot: Q9BY76

Calculated MW: 45kDa

Recommended dilution:
WB 1:500-2000, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.