ANKH Polyclonal Antibody

Background:
This gene encodes a multipass transmembrane protein that is expressed in joints and other tissues and controls pyrophosphate levels in cultured cells. Progressive ankylosis-mediated control of pyrophosphate levels has been suggested as a possible mechanism regulating tissue calcification and susceptibility to arthritis in higher animals. Mutations in this gene have been associated with autosomal dominant craniometaphyseal dysplasia.

Research Area: Signal Transduction

Synonyms:
ANKH, ANK, CCAL2, CMDJ, CPPDD, HANK, MANK

Immunogen: Recombinant fusion protein of human ANKH (NP_473368.1).

Swissprot: Q9HCJ1
Gene ID: 56172

Calculated MW: 32 kDa/54 kDa
Observed MW: 54 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.