ANKHD1 polyclonal, anti-human

Background:
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.

Synonyms: MASK, MASK1, PP2500, VBARP, ankyrin repeat and KH domain containing 1

Cellular Location: Cytoplasm 

Immunogen:
Recombinant protein of human ANKHD1

Gene Symbol: ANKHD1

Gene ID: 54882

Swiss prot: Q8IWZ3

Calculated MW: 60/65/269/277kDa

Recommended dilution:
IHC 1:50-200

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20°C. Avoid freeze / thaw cycles.