ANKHD1 Polyclonal Antibody

Background:
This gene encodes a protein with multiple ankyrin repeat domains and a single KH-domain. The protein is thought to function as a scaffolding protein, and it may be involved in the regulation of caspases and thereby play an antiapoptotic role in cell survival. Alternative splicing results in multiple transcript variants, one of which generates a fusion transcript (MASK-BP3) with the downstream eIF4E-binding protein 3 (EIF4EBP3) gene, resulting in a protein comprised of the ANKHD1 sequence for the majority of the protein and a different C-terminus due to an alternate reading frame for the EIF4EBP3 segments.

Research Area: Cancer, Cell Biology, Immunology

Synonyms:
ANKHD1, MASK, MASK1, PP2500, VBARP

Immunogen: Recombinant fusion protein of human ANKHD1 (NP_060217.1).

Swissprot: Q8IWZ3
Gene ID: 54882

Calculated MW: 59 kDa/63 kDa/64 kDa/269 kDa/277 kDa
Observed MW: 269 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.