ANKMY2 Polyclonal Antibody

Background:
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states.

Synonyms:
Ankmy2, ANKY2, Ankyrin repeat and MYND domain containing 2, Ankyrin repeat and MYND domain containing protein 2, Ankyrin repeat and MYND domain-containing protein 2, DKFZP564O043, OTTHUMP00000116019, OTTHUMP00000201684, ZMYND20

Immunogen: Recombinant protein of human ANKMY2

Swissprot: Q8IV38
Gene Accession: BC035353

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.2 mg/mL
Dilution: IHC 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-138102/sc-138103