ANKS1B polyclonal, anti-human, mouse, rat

Background:
This gene encodes a multi-domain protein that is predominantly expressed in brain and testis. This protein interacts with amyloid beta protein precursor (AbetaPP) and may have a role in normal brain development, and in the pathogenesis of Alzheimer's disease. Expression of this gene has been shown to be elevated in patients with pre-B cell acute lymphocytic leukemia associated with t(1;19) translocation. Alternatively spliced transcript variants encoding different isoforms (some with different subcellular localization, PMID:15004329) have been described for this gene.

Synonyms: AIDA, AIDA-1, ANKS2, EB-1, EB1, cajalin-2

Cellular Location: Cajal body Cell junction Cell projection Cytoplasm Nucleus dendritic spine postsynaptic cell membrane postsynaptic density synapse

Immunogen:
Recombinant protein of human ANKS1B

Gene Symbol: ANKS1B

Gene ID: 56899

Swiss prot: Q7Z6G8

Calculated MW: 138kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.