Ankyrin-1 polyclonal, anti-human
€422.00
In stock
SKU
252063
Protein Family: Cytoskeleton Proteins
Pathway and Disease: Signaling Molecules and Interaction
Description:
Ankyrin-1 attaches (ANK1) integral membrane proteins to cytoskeletal elements. Erythrocyte ankyrins link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein. Defects in ANK1 are a cause of spherocytosis type 1 (SPH1), also called hereditary spherocytosis type 1 (HS1). Spherocytosis is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. Inheritance can be autosomal dominant or recessive.
Alternate Names: Ankyrin-1, ANK-1, Erythrocyte ankyrin, Ankyrin-R, ANK1, ANK
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P16157
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ankyrin-1.
Format: Each vial contains 0.1 mg serum in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Pathway and Disease: Signaling Molecules and Interaction
Description:
Ankyrin-1 attaches (ANK1) integral membrane proteins to cytoskeletal elements. Erythrocyte ankyrins link spectrin (beta chain) to the cytoplasmic domain of the erythrocytes anion exchange protein. Defects in ANK1 are a cause of spherocytosis type 1 (SPH1), also called hereditary spherocytosis type 1 (HS1). Spherocytosis is a hematologic disorder leading to chronic hemolytic anemia and characterized by numerous abnormally shaped erythrocytes which are generally spheroidal. Inheritance can be autosomal dominant or recessive.
Alternate Names: Ankyrin-1, ANK-1, Erythrocyte ankyrin, Ankyrin-R, ANK1, ANK
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500
Accession No.: P16157
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human ankyrin-1.
Format: Each vial contains 0.1 mg serum in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
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