Annexin A2 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Annexin A2 also known as annexin II is a protein that in humans is encoded by the ANXA2 gene. The ANXA2 gene has three pseudogenes located on chromosomes 4, 9 and 10, respectively. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. This protein is a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions as an autocrine factor which heightens osteoclast formation and bone resorption. Richard et al.(1994) presented an integration of the physical, expression, and genetic maps of human chromosome 15. They placed the ANXA2 gene in their region IV, i.e., 15q21-q22, thus confirming the previous localization.

Description:
Rabbit IgG polyclonal antibody for Annexin A2 (ANXA2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.

Synonyms:
Annexin A2 antibody, Annexin II antibody, Annexin II, heavy chain antibody, Annexin-2 antibody, ANX 2 antibody, ANX2 antibody, ANX2L4 antibody, ANXA2 antibody, ANXA2_HUMAN antibody, arylsulfatase B antibody, CAL1H antibody, Calpactin I heavy chain antibody, calpactin I heavy polypeptide(p36) antibody, Calpactin-1 heavy chain antibody, chromobindin 8 antibody, Chromobindin-8 antibody, LIP2 antibody, Lipocortin II antibody, LPC2 antibody, LPC2D antibody, P36 antibody, P36 protein antibody, PAP-IV antibody, placental anticoagulant protein IV antibody, Protein I antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Annexin A2(121-141aa RAEDGSVIDYELIDQDARDLY), different from the rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.