Annexin A3 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Annexin A3 is a protein that in humans is encoded by the Annexin A3 gene. The Annexin A3 gene contains 13 exons and spans 58 kb of genomic DNA. The Annexin A3 gene is mapped to 4q21. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. This protein functions in the inhibition of phospholipase A2 and cleavage of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. This protein may also play a role in anti-coagulation.

Description:
Rabbit IgG polyclonal antibody for Annexin A3 (ANXA3) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.

Synonyms:
2-cyclic phosphate 2-phosphohydrolase antibody, 35-alpha calcimedin antibody, Annexin A3 antibody, Annexin III antibody, Annexin-3 antibody, ANX3 antibody, ANXA 3 antibody, Anxa3 antibody, ANXA3_HUMAN antibody, Inositol 1 2 cyclic phosphate 2 phosphohydrolase antibody, Inositol 1 antibody, Lipocortin III antibody, OTTHUMP00000160701 antibody, OTTHUMP00000219237 antibody, OTTHUMP00000219238 antibody, PAP III antibody, PAP-III antibody, Placental anticoagulant protein III antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human Annexin A3 (153-184aa RKALLTLADGRRDESLKVDEHLAKQDAQILYK), different from the related mouse sequence by one amino acid, and from the related rat sequence by three amino acids.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.