Annexin A3 polyclonal, anti-human, mouse, rat

Background:
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes and is characterized by a conserved core domain, which binds phospholipids in a Ca2+-dependent manner, and a unique amino-terminal region, which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis, exocytosis and cellular adhesion. Annexin III, also known as ANXA3, Annexin A3, Lipocortin III, PAP-III (placental anticoagulant protein III), 35-α calcimedin or ANX3, belongs to the annexin family and contains four Annexin repeats. Annexin III exhibits a variety of functions, including anti-coagulent properties, an inhibitory role towards phospholipase A2 (PLA2) and an enzymatic function, cleaving the cyclic bond of inositol 1,2-cyclic phosphate to produce inositol 1-phosphate.

Alternative Name:
PAP-III, ANXA3, ANX3, 2-cyclic phosphate 2-phosphohydrolase, 35-alpha calcimedin, Annexin A3, Annexin III, Annexin-3, ANX3, ANXA 3, Anxa3, ANXA3, Calcimedin 35 alpha, Inositol 1 2 cyclic phosphate 2 phosphohydrolase, Inositol 1, Lipocortin III, OTTHUMP00000160701, OTTHUMP00000219237, OTTHUMP00000219238, PAP III, PAP-III, Placental anticoagulant protein III,

Application Dilution:
WB:1:500-1:2,000
IHC:1:50-1:200
FC:1:50-1:100

Specificity: Annexin A3 polyclonal antibody detects endogenous levels of Annexin A3 protein.

Immunogen:
Recombinant protein with Human Annexin A3 aa 1-350.

MW: 36 kDa

Swiss-Prot: P12429(Human) O35639(Mouse) P14669(Rat)

Purification & Purity:
Protein affinity purified.

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.