Annexin IV polyclonal, anti-human

Background:
The annexin family of calcium-binding proteins is composed of at least ten mammalian genes. It is characterized by a conserved core domain which binds to phospholipids in a Ca++-dependent manner and a unique amino terminal region which may confer binding specificity. Annexin family members have been implicated as regulators of such diverse processes as ion flux, endocytosis and exocytosis, and cellular adhesion. For example, the crystal structure of Annexin III has suggested a hydrophilic amino terminus with possible Ca++ channel activity. Similarly, Annexin V has ion channel properties. Annexin IV, also referred to as endonexin, functions to regulate Cl- flux by mediating calmodulin kinase II (CaMKII) activity and Annexin V has been shown to regulate PKC activity.

Alternative Name:
PAP-II, ANXA4, ANX4, 35 beta calcimedin, 35-beta calcimedin, AIV, Annexin 4, Annexin A4, Annexin IV (placental anticoagulant protein II), Annexin IV, Annexin IV placental anticoagulant protein II, Annexin-4, AnnexinA4, AnnexinIV, ANX 4, ANX A4, ANX4, ANXA 4, ANXA4, ANXA4 protein, ANXA4, Carbohydrate binding protein P33/P41, Carbohydrate-binding protein p33/p41, Chromobindin 4, Chromobindin-4, Chromobindin4, DKFZp686H02120, Endonexin I, EndonexinI, Lipocortin IV, LipocortinIV, MGC75105, OTTHUMP00000160052, OTTHUMP00000202207, P32.5, P33/41, PAP II, PAP-II, PAPII, PIG 28, PIG28, Placental anticoagulant protein II, PP4 X, PP4-X, PP4X, Proliferation inducing gene 28, Proliferation inducing protein 28, Protein II, Xanx-4, ZAP 36, ZAP36,

Application Dilution:
WB:1:500-1:2,000
ICC/IF:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: Annexin IV polyclonal antibody detects endogenous levels of Annexin IV protein.

Immunogen:
Recombinant protein within human Annexin IV aa 1-200.

MW: 36 kDa

Swiss-Prot: P09525(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.