ANP polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Atrial natriuretic peptide (ANP), also known as NPPA or PND, is a powerful vasodilator, and a protein (polypeptide) hormone secreted by heart muscle cells. This gene is mapped to 1p36.22. It is involved in the homeostatic control of body water, sodium, potassium and fat (adipose tissue). ANP is released by muscle cells in the upper chambers (atria) of the heart (atrial myocytes) in response to high blood volume. It acts to reduce the water, sodium and adipose loads on the circulatory system, thereby reducing blood pressure. ANP has exactly the opposite function of the aldosterone secreted by the zona glomerulosa in regard to its effect on sodium in the kidney – that is, aldosterone stimulates sodium retention and it generates sodium loss.

Description:
Rabbit IgG polyclonal antibody for Natriuretic peptides A (NPPA) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
ANF antibody, ANF_HUMAN antibody, ANP antibody, ATFB6 antibody, Atrial natriuretic factor antibody, Atrial natriuretic factor precursor antibody, Atrial natriuretic peptide antibody, Atriopeptin antibody, Cardionatrin antibody, CDD ANF antibody, CDD-ANF antibody, CDP antibody, Natriuretic peptide A antibody, Natriuretic Peptide Precursor A antibody, NPPA antibody, PND antibody, Prepronatriodilatin antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human ANP(124-151aa SLRRSSCFGGRMDRIGAQSGLGCNSFRY), different from the related mouse and rat sequences by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of human ANP(124-151aa SLRRSSCFGGRMDRIGAQSGLGCNSFRY), different from the related mouse and rat sequences by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse, rat.
Predicted to work with: human.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.