ANP32E polyclonal (N-term), anti-human
€235.00
In stock
SKU
AC-AP21521a-ev
Catalog Number: AC-AP21521a-ev
Size: 80 µl
Isotype: Rabbit IgG
Clone Name: RB49728
Applications: WB
Datasheet
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Size: 80 µl
Isotype: Rabbit IgG
Clone Name: RB49728
Applications: WB
Datasheet
Request Information
Background:
Histone chaperone that specifically mediates the genome- wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.
Other Names:
Acidic leucine-rich nuclear phosphoprotein 32 family member E, LANP-like protein, LANP-L, ANP32E
Target/Specificity:
This ANP32E antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-64 amino acids from the N-terminal region of human ANP32E.
Gene Name: ANP32E
Gene ID: 81611
Primary Accession: Q9BTT0
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Histone chaperone that specifically mediates the genome- wide removal of histone H2A.Z/H2AFZ from the nucleosome: removes H2A.Z/H2AFZ from its normal sites of deposition, especially from enhancer and insulator regions. Not involved in deposition of H2A.Z/H2AFZ in the nucleosome. May stabilize the evicted H2A.Z/H2AFZ-H2B dimer, thus shifting the equilibrium towards dissociation and the off-chromatin state (PubMed:24463511). Inhibits activity of protein phosphatase 2A (PP2A). Does not inhibit protein phosphatase 1. May play a role in cerebellar development and synaptogenesis.
Other Names:
Acidic leucine-rich nuclear phosphoprotein 32 family member E, LANP-like protein, LANP-L, ANP32E
Target/Specificity:
This ANP32E antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 31-64 amino acids from the N-terminal region of human ANP32E.
Gene Name: ANP32E
Gene ID: 81611
Primary Accession: Q9BTT0
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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