ANPEP/CD13 monoclonal, anti-human
€0.00
In stock
SKU
AC-AM2079b
Catalog Number: AC-AM2079b
Size: 80 µl, 400 µl
Isotype: mouse IgG2a
Clone Name: 505CT12.1.2
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG2a
Clone Name: 505CT12.1.2
Applications: WB
Datasheet
Request Information
Background:
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. Inthe small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-bindingmetalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Other Names:
Aminopeptidase N, AP-N, hAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, gp150, CD13, ANPEP, APN, CD13, PEPN
Target/Specificity:
This ANPEP/CD13 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from human ANPEP/CD13.
Antigen Region:
156-184
Antigen Type: Synthetic Peptide
Gene Name: ANPEP
Gene ID: 290
Primary Accession: P15144
NCBI Accession: NP_001141.2
Other Accession: NP_001141.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Aminopeptidase N is located in the small-intestinal and renal microvillar membrane, and also in other plasma membranes. Inthe small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-bindingmetalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types, including small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma.
Other Names:
Aminopeptidase N, AP-N, hAPN, Alanyl aminopeptidase, Aminopeptidase M, AP-M, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13, gp150, CD13, ANPEP, APN, CD13, PEPN
Target/Specificity:
This ANPEP/CD13 antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 156-184 amino acids from human ANPEP/CD13.
Antigen Region:
156-184
Antigen Type: Synthetic Peptide
Gene Name: ANPEP
Gene ID: 290
Primary Accession: P15144
NCBI Accession: NP_001141.2
Other Accession: NP_001141.2
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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